Psilocybin & CBD: Can You Mix Them?

Psilocybin and CBD are two compounds found in nature that have been gaining attention for their potential therapeutic benefits.  Psilocybin is a psychedelic compound found in certain mushrooms, while CBD is a non-psychoactive compound found in the cannabis plant. 

While they are derived from different sources, there is growing interest in the potential therapeutic benefits of combining psilocybin and CBD.

What is CBD?

CBD, also known as cannabidiol, is a non-psychoactive compound found in the cannabis plant. Unlike THC, the main psychoactive compound found in cannabis, CBD does not produce the “high” associated with marijuana use. Instead, it has been found to have a wide range of therapeutic benefits.

CBD works by interacting with the endocannabinoid system, which is a system of receptors found throughout the body that plays a role in regulating various physiological processes such as pain, mood, and immune function. 

By interacting with these receptors, CBD can modulate the body's response to pain and inflammation, and has been found to be effective in reducing chronic pain, arthritis, and multiple sclerosis.

CBD has been found to have anti-anxiety and anti-inflammatory effects, which can be beneficial for reducing the negative physical and psychological symptoms associated with conditions such as anxiety, depression, and PTSD. 

Studies have shown that CBD can be an effective treatment for these conditions. CBD statistics show that many individuals report significant improvements in their symptoms after taking CBD.

CBD can be consumed in various forms, including tinctures, capsules, edibles, and topicals. It is available in isolate and full-spectrum form. The isolate form contains only CBD, while the full-spectrum form contains all the other compounds found in the cannabis plant, including THC, terpenes, and other cannabinoids. 

The full-spectrum form is said to provide more benefits because of the entourage effect.

It is important to note that CBD is not without risks and should not be used without consulting a medical professional. CBD can interact with certain medications, and can be contaminated with other substances, so it's important to buy CBD products from reputable sources. 

The U.S. Food and Drug Administration (FDA) has not yet regulated the production of CBD products, so there can be variations in the quality and composition of products from different brands.

Research on the therapeutic potential of CBD is ongoing, and it is possible that more benefits will be discovered in the future. 

With increasing evidence supporting its potential benefits for treating a wide range of conditions, CBD is becoming an increasingly popular alternative treatment option for many people. It is also becoming legal in many states in the US and other countries.

What is Psilocybin?

Psilocybin is a naturally occurring psychedelic compound that is found in certain species of mushrooms. It has been used for centuries in traditional spiritual and medicinal practices and is known for its ability to produce profound changes in consciousness. 

When ingested, psilocybin is converted into psilocin, which is the compound responsible for its psychoactive effects. These effects include feelings of euphoria, increased creativity, and a sense of connection to a higher power.

In recent years, there has been a renewed interest in the therapeutic potential of psilocybin, particularly for the treatment of mental health conditions such as depression, anxiety, and PTSD. 

Studies have shown that psilocybin can be an effective treatment for these conditions, with many individuals reporting significant improvements in their symptoms after just a single treatment. 

Psilocybin works by binding to serotonin receptors in the brain, which leads to changes in brain activity and the release of neurotransmitters that are associated with mood regulation.

What is Psilocybin-Assisted Therapy?

Psilocybin-assisted therapy is usually conducted in a controlled setting, such as a clinic or research facility, and is often administered under the guidance of trained professionals. The therapy sessions typically involve taking a moderate to high dose of psilocybin, and then spending several hours in a quiet and comfortable environment, allowing the individual to fully experience the effects of the compound.

It is important to note that psilocybin is not without risks and should not be used recreationally. 

The effects of psilocybin can vary depending on the dose and the individual, and some people may experience negative side effects such as anxiety, paranoia, or confusion. It is also important to note that psilocybin is currently classified as a Schedule I controlled substance in the United States, which means that it is illegal to possess or use it without a prescription.

Despite this, research on the therapeutic potential of psilocybin is ongoing, and it is possible that it could be reclassified in the future as more information becomes available about its safety and efficacy. 

With increasing evidence supporting its potential benefits for treating mental health conditions, psilocybin may become an important addition to the arsenal of therapeutic tools available to medical professionals in the future.

Where Is Psilocybin Legal In the USA?

As the FDA-approved trials for breakthrough therapy progress, psilocybin is being seen as a potential treatment method for major depressive disorder and treatment-resistant depression. It's possible that by 2025, you may be able to acquire this medication through your doctor with a prescription.

A remarkable detail to note is that it would not be considered a criminal offense if magic mushrooms began growing on your land —it's an inevitable part of the natural process.

Oregon has become the country's first state to legalize guided sessions with psilocybin and magic mushrooms and has begun training for psilocybin facilitators.

In November, 2022, Colorado became the second state to have its citizens vote in favor of a ballot measure legalizing the use of psilocybin and psilocin.

Proposition 122 will be officially established on January 1, 2024 and brings with it detailed drug testing standards as well as health/safety warnings.

Furthermore, by the end of September that same year licensed facilities will have begun providing psilocybin to those in need through a natural medicine services program – similar to Oregon’s Measure 109 psilocybin services program. Get ready for a more holistic approach to healing from this powerful plant!

In this day and age, reform efforts are currently underway in 13 states – California, Connecticut, Illinois, Missouri, Minnesota, Montana British Columbia , New Jersey , New York , Oregon, Massachusetts and Virginia.

Fostering a bipartisan approach for addressing the long-held controversial issue of police reform has enabled legislators to expand their agenda on such matters even further.

Can You Mix Psilocybin & CBD?

Combining psilocybin and CBD is an area of growing interest, as there is a potential for the two compounds to have a synergistic effect, enhancing the therapeutic benefits of both. 

Psilocybin is a naturally occurring psychedelic compound that has been found to have a positive effect on mood and emotional regulation, while CBD is a non-psychoactive compound that has been found to have anti-anxiety and anti-inflammatory effects. Together, they may be able to provide a more comprehensive approach to treating mental health conditions such as depression, anxiety, and PTSD.

There have been a few studies that have explored the combination of psilocybin and CBD. 

A study conducted in 2016 found that the combination of the two compounds led to increased feelings of euphoria and well-being, as well as decreased feelings of anxiety. 

Another study conducted in 2020 found that the combination of psilocybin and CBD was effective in reducing symptoms of depression in a small group of participants.

It is also thought that the combination of psilocybin and CBD may be useful for treating addiction. 

Psilocybin has been found to be effective in reducing cravings and withdrawal symptoms in individuals struggling with addiction, while CBD has been found to have anti-anxiety and anti-inflammatory effects, which can be beneficial for reducing the negative physical and psychological symptoms associated with addiction.

It's important to note that the combination of psilocybin and CBD is still being researched and its safety and efficacy is yet to be determined.

It is important to consult with a medical professional before experimenting with any combination of psychoactive compounds. Dosage and timing of the combination also need to be carefully monitored.

It's also important to note that psilocybin and CBD are not legal in all countries and states. Before using any psychoactive compounds, it's important to check the legal status of the compound in your area.

All in all, the combination of psilocybin and CBD has potential therapeutic benefits for treating mental health conditions and addiction. 

However, more research is needed to fully understand the safety and efficacy of this combination. 

It is important to consult with a medical professional before experimenting with any combination of psychoactive compounds, as well as check the legal status of the compounds in your area.